AETIOLOGY OF PROLONGED APNOEA AFTER SUXAMETHONIUM
نویسندگان
چکیده
منابع مشابه
Prolonged apnoea after suxamethonium in a Malaysian patient due to silent plasma cholinesterase--first case report.
A bnormal variants of plasma cholinesterase (ChE, EC. 3.1.1.8) are a rarity in this region and to date there is no reported case of suxamethonium sensz#vity in the Malaysian population. We now report a case of a Malaysian Indian patient who received suxamethonium, developed prolonged apnoea and on investigation was found to be a homozygote for the silent gene. His family was screened for abnorm...
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The neuromuscular blockade produced by a prolonged (greater than 90 min) continuous infusion of suxamethonium and measured with train-of-four stimulation was studied in 20 infants and 20 children during nitrous oxide and halothane in oxygen anaesthesia. The results were compared with a previous study in adults. Suxamethonium requirement was increased in infants and children. Mean peak infusion ...
متن کاملPrevention, diagnosis and treatment of prolonged apnoea.
T H E increasing understanding of the mechanism of action of the muscle relaxants has led to a high degree of safety in their use. Nevertheless, the occasional patient is still encountered in whom the response to the drug is greater than anticipated. There are already a number of reports in the literature outlining the almost unlimited number of causes for this prolonged response (Paton, 1958; ...
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The use of suxamethonium chloride by intramuscular injection as a short acting muscle relaxant for endotracheal intubation is described. The incidence and severity of postoperative muscle pains in this group of 94 patients is compared with the results of another group (of 112 patients) in which the drug was given intravenously. The incidence of pains was similar in the two groups (26.6 and 28.6...
متن کاملApnoea following suxamethonium: the genetic study of four generations of a family.
Nineteen subjects were investigated as a result of apnoea following the administration of suxamethonium occurring in one member of the family. Examination of the blood for cholinesterase activity, dibucaine number, and fluoride number was carried out and the appropriate genotype determined. The significance of the genetic variation of plasma cholinesterase in relation to suxamethonium apnoea is...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1974
ISSN: 0007-0912
DOI: 10.1093/bja/46.4.273